WSU DLCL2(人淋巴瘤細胞)
CBP60273
                       
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                | I. General information | |
| Synonyms: | WSU DLCL2 | 
| Background: | derived from the pleural effusion of a 41-year-old Caucasian man with B-cell non-Hodgkin lymphoma (B-NHL, diffuse large cell lymphoma non-cleaved type, intermediate grade - transformed from follicular small cleaved cell, low grade) at the status of relapse/progressive disease in 1990; cell line carries EZH2 Y641F mutation | 
| Species: | human (Homo sapiens) | 
| Tissue: | N/A | 
| Disease: | B cell lymphoma | 
| Gender: | N/A | 
| Morphology: | round and oval cells growing singly or in small clumps in suspension; | 
| Growth Mode: | N/A | 
| Doubling Time: | ca. 50-70 hours | 
| DNA Profile: | N/A Our Cell Line Authentication Service | 
| Culture Medium: | RPMI-1640+10%FBS WSU DLCL2完全培養(yǎng)基,# CBP60273M | 
| Cryopreservation medium: | 90%FBS+10%DMSO | 
| Mycoplasma: | contamination was eliminated with Plasmocin, then negative in microbiological culture, PCR assays | 
| Immunology: | CD3 -, CD10 +, CD13 -, CD19 +, CD20 +, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 -, CD 138 -, HLA-DR +, sm/cyIgG +, sm/cyIgM -, sm/cykappa -, sm/cylambda +; image | 
| Fingerprint: | fluorescent nonaplex PCR of short tandem repeat markers revealed a unique DNA profile | 
| Species: | confirmed as human by cytogenetics and species PCR | 
| Cytogenetics: | human hyperdiploid karyotype - 47(43-48)<2n>XY, +7, +8, t(1;2)(p36;q37), del(3)(q25), t(4;14)(q27;q31), der(7)t(3;7)(q25;p13), i(7p), add(8)(q24)x2, del(13)(?q21?q22), t(14;18)(q32;q21), del(15)(q25q27) - carries t(14;18) effecting BCL2-IGH fusion - matches published karyotype | 
| Virus | PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/II -, MLV -, SMRV - | 
| Comments: | For more information, please contact us (4008-750-250). | 
 
            
 
             
             
         
             
             
             
             
             
             
            