hFGFR2b/MC-38
CBPG0206
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
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FGFR2B 是成纖維細(xì)胞生長因子受體 2（FGFR2）的剪接變體之一，屬于受體酪氨酸激酶（RTK）家族，由胞外配體結(jié)合域（含三個(gè)免疫球蛋白樣結(jié)構(gòu)域）、跨膜區(qū)及胞內(nèi)酪氨酸激酶域組成。其特異性由外顯子 IIIb 的選擇性剪接決定，主要在上皮細(xì)胞表達(dá)，與間質(zhì)細(xì)胞來源的 FGFR2C（IIIc 剪接變體）形成旁分泌信號(hào)軸，調(diào)控上皮-間質(zhì)相互作用。
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II. Introduction
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Host Cell:
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MC-38
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Expressed gene:
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hFGFR2b
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Stability:
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32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
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Freeze Medium:
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90% FBS+10% DMSO
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Culture Medium:
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DMEM+10%FBS+2μg/ml Puromycin
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Mycoplasma Testing:
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Negative
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Storage:
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Liquid nitrogen
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III. Description of Host Cell Line
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Organism:
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Mus musculus, mouse
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Tissue:
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Colon
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Morphology:
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Epitheloid cell
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Growth Properties:
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Adherent
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IV. Representative Data
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