S154-STING-KI ISRE-Luc NFκB-SEAP THP-1
CBP74218
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| I. Background | |
| Different innate immune pathways converge to Stimulator of interferon genes (STING) and trigger type I interferon responses after recognition of abnormal nucleic acids in the cells. This non-redundant function renders STING a major player in immunosurveillance, and an emerging target for cancer and infectious diseases therapeutics. | |
| II. Introduction | |
| Host Cell: | THP-1 |
| Expressed gene: | S154-hSTING-KI |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+ 2 mM L-glutamine+ 25 mM HEPES+ 10%FBS+ 100 µg/ml Normocin+ Pen-Strep (100 U/ml-100 µg/ml) |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Homo sapiens, human |
| Tissue: | peripheral blood |
| Disease: | acute monocytic leukemia |
| Morphology: | monocyte |
| Growth Properties: | suspension |
| IV. Representative Data | |
